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The province of Aceh has a crop diversity that has the potential to be developed as a medicine. The plants are the barks of Dyera costulata, barks of Lannea coromandelica and the of Vitex pinnata Linn leaves. Ditermine analysis antioxidant activity with 2,2 diphenyl-picrylhydrazyl (DPPH) and as a positive control used vitamin C (ascorbit acid). The result of antioxidant activity test in methanol extract showed that IC50 (Inhibition Concentration) value for barks of Lannea coromandelica 6.11, IC50 for Vitex pinnata Linn leaves 19.05 and IC50 values for barks of Dyera costulata 19.59. Of the three types of medicinal plants tested for their antioxidant activity, the bark of the Lannea glandis has the best antioxidant activity with IC50 of 6.11. IC50 vitamin C (ascorbat acid) 4,56.